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Learning module: Thematic trip active ingredients
The Active Ingredients themed tour deals with the methods and techniques that have been used to develop new active ingredients and drugs over the past 100 to 150 years and those that are still used today. In order to illustrate the historical advancement in drug research and development, three very successful active ingredients of the past century are described in detail with regard to their development history and mode of action: the pain reliever aspirin, the ulcer therapeutic agent cimetidine and, using the example of zanamivir, the new generation of antiviral flu drugs.
The differences between historical and modern drug development, i.e. the way from trial and error (Aspirin) to the rational design of new drugs with the help of the most modern computer processes, chemical-analytical methods and microbiological techniques (Zanamivir). Cimetidine forms the link on this path and shows how rational methods have gradually found their way into drug research and how they have contributed to discovering more effective drugs through targeted variation of lead structures.
- Target groups
- In accordance with the pronounced interdisciplinary nature of this module, the Active Ingredients theme trip is aimed at chemists, biochemists, biologists, molecular biologists, virologists, pharmacists, medical professionals and others. The introductory pages to the individual examples in particular contain information that is understandable and interesting for laypeople.